News of World Medicine

Scientists have determined an "ultra-bad" form of cholesterol

Scientists have determined a new "ultra-bad" form of low-density lipoprotein (LDL) in people with high risk of the development of cardiovascular diseases.

British scientists have found out that this type of cholesterol, which is called MGmin-LDL (minimally modified by methylglyoxal), it steaks to artery walls easily and form plaques, which promotes arterial occlusion and increased risk of infraction and stroke development.

This founding explains why diabetic patients have an increased risk of the development of coronary heart disease. Scientists hope that the results obtained will help in developing of new treatment methods.

During investigation process scientists have managed to create MGmin-LDL in the laboratory by glycosylation (adding sugar groups to normal levels of LDL, known as "bad" cholesterol). In the result, the form of LDL has changed - cholesterol has become stickier, and it promotes plaque formation, narrowing of arterial ducts and worsening of blood circulation.

The researches are sure that this founding will help in developing of treatment methods for coronary heart disease, especially in elderly patients and patients with type 2 diabetes mellitus. 


Adopted from: HealthFinder